General Information

  • ID:  hor000617
  • Uniprot ID:  P82158
  • Protein name:  Cydiastatin-7
  • Gene name:  NA
  • Organism:  Cydia pomonella (Codling moth)
  • Family:  Allatostatin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Cydia (genus), Grapholitini (tribe), Olethreutinae (subfamily), Tortricidae (family), Tortricoidea (superfamily), Apoditrysia, Ditrysia, Heteroneura (parvorder), Neolepidoptera (infraorder), Glossata (suborder), Lepidoptera (order), Amphiesmenoptera (superorder), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  KMYDFGL
  • Length:  7(1-7)
  • Propeptide:  KMYDFGL
  • Signal peptide:  NA
  • Modification:  T7 Leucine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000617_AF2.pdbhor000617_ESM.pdb

Physical Information

Mass: 98024 Formula: C41H60N8O11S
Absent amino acids: ACEHINPQRSTVW Common amino acids: DFGKLMY
pI: 6.34 Basic residues: 1
Polar residues: 2 Hydrophobic residues: 2
Hydrophobicity: -8.57 Boman Index: -322
Half-Life: 1.3 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 55.71
Instability Index: 11202.86 Extinction Coefficient cystines: 1490
Absorbance 280nm: 248.33

Literature

  • PubMed ID:  9392829
  • Title:  Lepidopteran Peptides of the Allatostatin Superfamily